• CRISPRi screens reveal sources of metabolic robustness in E. coli November 24, 2020
    Metabolic robustness, the ability of a metabolic system to buffer changes in its environment, is not always a welcome feature for microbiologists: it interferes with metabolic engineering or prevents that antibiotics kill bacteria. Therefore it is important to understand the mechanisms that enable metabolic robustness. A massively parallel CRISPRi screen demonstrated that E. colimetabolism is […]
  • Popular weight-loss surgery in teenagers weakens bones November 24, 2020
    A common weight loss surgery for adolescents with obesity called sleeve gastrectomy has harmful effects on bones, according to a new study.
  • Age is no barrier to successful weight loss November 20, 2020
    Obese patients over the age of 60 can lose an equivalent amount of weight as younger people using only lifestyle changes, according to a new study that demonstrates that age is no barrier to losing weight.
  • Are high-protein total diet replacements the key to maintaining healthy weight? November 18, 2020
    The results of a new study suggest that high-protein total diet replacements are a promising nutritional strategy to combat rising rates of obesity. In particular, the study provides further evidence that diets with a higher proportion of protein might offer a metabolic advantage compared to a diet consisting of the same number of calories, but […]
  • Masks don't impair lung function during physical activity, study finds November 16, 2020
    While they might feel uncomfortable, facemasks do not significantly change the actual work of breathing or the flow of oxygen and carbon dioxide when worn while exercising, researchers report.
  • Bursts of exercise can lead to significant improvements in indicators of metabolic health November 16, 2020
    Short bursts of physical exercise induce changes in the body's levels of metabolites that correlate to, and may help gauge, an individual's cardiometabolic, cardiovascular and long-term health, a study has found. Approximately 12 minutes of acute cardiopulmonary exercise impacted more than 80% of circulating metabolites, including pathways linked to a range of favorable health outcomes, […]